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SCD Case Study of 50 Patients/Remission (Rush University in Chicago)

July 26, 2015

The Journal of the Academy of Nutrition and Dietetics has just published a case study of 50 Crohn's Disease (CD) and ulcerative colitis (UC) patients on the SCD. This is the largest case study of SCD patients so far. Here are the highlights:

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  • The patients had their IBD diagnoses confirmed
  • All patients were in remission
  • Average age 36, range was from 10 to 66
  • "Real-world" conditions with patients regarding medications and compliance.
    • 36 patients with CD; 19 with no meds
    • 9 patients UC; 1 patient no meds
    • 5 patients indeterminate disease (couldn't tell if CD or UC); 2 patients no meds
  • Medications dropped. Of the 22 people on no meds who remained in remission:
    • 16 had discontinued steroids
    • 3 had stopped TNF inhibitors (which include Remicade, Humira, etc)
    • 5 had been on 6-MP
  • See the full study for details on current medications (includes over a dozen people using mesalamine)

The study's authors conclude that:

We now show that at least a subgroup of patients with IBD may notably improve as a result of following the SCD and/or dietary interventions in general. [emphasis added]

In addition, they write:

... this may be a low-cost intervention to induce and maintain remission with little or no known adverse reactions. As such, further interventional studies of SCD and diet therapies in general for IBD are urgently needed. [emphasis added]

Kakodkar, S., Farooqui, A. J., Mikolaitis, S. L., & Mutlu, E. a. (2015). The Specific Carbohydrate Diet for Inflammatory Bowel Disease: A Case Series. Journal of the Academy of Nutrition and Dietetics, 115(8), 1226–1232. doi:10.1016/j.jand.2015.04.016

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